منابع مشابه
Histochemistry of B663 Pigmentation: Ceroid-Like Pigmentation
Since its use was first reported by 8rowne and Hogerzeil in 1962 ('0. /I), 8663, a synthesized phenazine dye, has proven to be an effective drug in the treatment of human leprosy and its use has become worldwide ( 2.7.9 " . 26. 3~. 39. 52. 5.1 ). The most significant and frequent side effect of this compound is an abnormal skin coloration. This can be divided into two types. One is an initial r...
متن کاملOral pigmentation
Change in color of oral mucosa reflects the underlying health status, which is either local or systemic. This color change is due to pigmentation, which may be physiological or pathological. Pigmentation in pathological conditions range from localized anomalies of to potentially life-threatening conditions. Since the dental professionals encounter a number of pigmented lesions in the oral cavit...
متن کاملOral Pigmentation and Intestinal Polyposis
IN 1921 Peutz described a family with intestinal polyposis and spots of melanin pigmentation in and around the mouth. Prior to this, in 1896, Sir Jonathan Hutchinson described two girls with pigmented patches in the oral mucosa and around the mouth. Later, Parkes Weber (1919) reported that one of these twins died of what appeared to be an intussusception. Since 1921 over one hundred cases have ...
متن کاملCushing's syndrome and skin pigmentation.
the appendage biopsy results failed to give any indication of prognosis. In two of our cases the comment had been made at the first operation that " it would not be surprising if the rheumatic process were still active," and in these two cases the appendage biopsies showed numerous Aschoff bodies suggesting continued rheumatic activity. Another patient had several attacks of subacute rheumatism...
متن کاملGenetic disorders of pigmentation.
More than 127 loci are actually known to affect pigmentation in mouse when they are mutated. From embryogenesis to transfer of melanin to the keratinocytes or melanocytes survival, any defect is able to alter the pigmentation process. Many gene mutations are now described, but the function of their product protein and their implication in melanogenesis are only partially understood. Each geneti...
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ژورنال
عنوان ژورنال: Nature
سال: 1910
ISSN: 0028-0836,1476-4687
DOI: 10.1038/083294a0